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The endothelium is permeableto small hydrophobic (lipid-soluble) molecules (e.g.,oxygen, carbon dioxide) that readily pass through thelipid bilayer of the endothelial cell membrane (a processcalled simple diffusion). A frequent observation of physicianssuch as Kubler-Ross or Hinton is that people do not commonly experience a“crisis of distress” in their final moments. All passes are identical as a group and all failures are identical as agroup with respect to performance on the screening test. The mutations were present in both full-length p53 and p53?,leading to the conclusion that oncogenic properties induced by a mutation in TP53are not simply transferred to a shorter p53 isoform. Kinsbourne (ed.), Asymmetrical Function ofthe Brain. (1988) Clinico-pathologic studies indementia: nondemented subjects with pathologically confi rmedAlzheimer’s disease.

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Parasitic tape-worm infections also produce clinical symptoms of perniciousanemia. The lifetime fracture prevalence exceeded 50% in middle-agedmen and 40% in women over the age of 75 years.

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