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It is also quite sobering to real-ize that, even in the context of the best possible preventa-tive efforts, all one can do is delay the onset of a major diseaseof aging: Eventually, we will all succumb to one of these mani-festations of aging. Tissue levels above the minimal inhibi-tory concentration (MIC) of skin microorganisms should be reached at the time or veryclose to the time of incision [116]. There are two sources ofcoenzyme Q10 – endogenous and exogenous

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In ASA 3–5 patients, IV catheters are placed without sedation, and fluids aregiven prior to anesthesia to correct electrolyte abnormalities and stabilize hemodynamicparameters. In addition, they reduce expiratory?ow through post-inspiratory activity of the dia-phragm and inspiratory chest wall muscles (Koschand Stark 1984) (Fig

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Probabilistic risk assessmentscan provide a description of the variability of risks within thepopulation and quantitative estimates of uncertainty associatedwith those risks.
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